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Heart Disease: 5 Differences in Men and Women

Heart disease differs between men and women in terms of cholesterol buildup because men tend to develop atherosclerosis. Here are 5 differences in heart disease for men and women.

1. Cholesterol buildup in different areas

Additionally, men tend to have higher levels of low-density lipoprotein (LDL) cholesterol, associated with plaque buildup in larger arteries. In comparison, women tend to have higher levels of high-density lipoprotein (HDL) cholesterol, associated with removing excess cholesterol from the body and protecting against heart disease.

2. Different symptoms of a heart attack

Heart disease differs between men and women in terms of heart attack symptoms because women may experience symptoms less typical of a heart attack, such as nausea, vomiting, back or jaw pain, and shortness of breath. In contrast, men are more likely to experience classic symptoms such as chest pain or pressure. 

Women may also have heart attacks at a later age than men and are more likely to have a heart attack due to non-obstructive coronary artery disease, which can be more challenging to diagnose. As a result, heart disease may be underdiagnosed and undertreated in women compared to men.

3. Differences in biology

Heart disease differs between men and women in terms of biology due to several factors, including differences in hormone levels, genetics, and anatomical features. For example, women have smaller coronary arteries than men, making them more prone to blockages. Additionally, estrogen provides some protective effects on the heart, but this protection decreases after menopause. 

4. Differences in diagnostic care

In diagnostic care, heart disease differs between men and women due to several factors, including differences in symptoms and risk factors. Women may present with atypical symptoms, such as fatigue or shortness of breath, which can be overlooked or misdiagnosed. 

5. Differences in treatment

Heart disease may differ in treatment and diagnosis between men and women because women may have different symptoms, risk factors, and anatomy compared to men.

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